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Notably, some secondary bile acids can cross the BBB, where they may directly impair neuronal function and exacerbate neurodegenerative processes

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It would appear from our findings that the minimum adequate intake values determined in a VA setting in older people by Tuttle et al [6] may closer to being accurate than those currently accepted as the RDA

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Relevant medications include etoposide, paclitaxel, vinblastine, vincristine, vindesine, antifungal agents, protease inhibitors, cimetidine, ranitidine, corticosteroids, erythromycin, fexofenadine, cyclosporine, loperamide, quinidine and others